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Orm Proteins Integrate Multiple Signals to Maintain Sphingolipid Homeostasis
Sphingolipids are structural components of membranes, and sphingolipid metabolites serve as signaling molecules. The first and rate-limiting step in sphingolipid synthesis is catalyzed by serine palmitoyltransferase (SPT). The recently discovered SPT-associated proteins, Orm1 and Orm2, are critical...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711311/ https://ncbi.nlm.nih.gov/pubmed/23737533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472860 |
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