Enhanced Fasting Glucose Turnover in Mice with Disrupted Action of TUG Protein in Skeletal Muscle

Insulin stimulates glucose uptake in 3T3-L1 adipocytes in part by causing endoproteolytic cleavage of TUG (tether containing a ubiquitin regulatory X (UBX) domain for glucose transporter 4 (GLUT4)). Cleavage liberates intracellularly sequestered GLUT4 glucose transporters for translocation to the ce...

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Main Authors: Löffler, Michael G., Birkenfeld, Andreas L., Philbrick, Katerina M., Belman, Jonathan P., Habtemichael, Estifanos N., Booth, Carmen J., Castorena, Carlos M., Choi, Cheol Soo, Jornayvaz, Francois R., Gassaway, Brandon M., Lee, Hui-Young, Cartee, Gregory D., Philbrick, William, Shulman, Gerald I., Samuel, Varman T., Bogan, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Metabolism
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711282/
https://ncbi.nlm.nih.gov/pubmed/23744065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458075
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