The Novel Cannabinoid CB(1) Receptor Neutral Antagonist AM4113 Suppresses Food Intake and Food-Reinforced Behavior but Does not Induce Signs of Nausea in Rats

Drugs that interfere with cannabinoid CB1 transmission suppress various food-motivated behaviors, and it has been suggested that such drugs could be useful as appetite suppressants. Biochemical studies indicate that most of these drugs assessed thus far have been CB1 inverse agonists, and although t...

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Autori principali: Sink, Kelly S, McLaughlin, Peter J, Wood, Jodi Anne T, Brown, Cara, Fan, Pusheng, Vemuri, V Kiran, Pang, Yan, Olzewska, Teresa, Thakur, Ganesh A, Makriyannis, Alex, Parker, Linda A, Salamone, John D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711240/
https://ncbi.nlm.nih.gov/pubmed/17581535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1301476
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