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N-Terminal Fragment of c-FLIP(L) Processed by Caspase 8 Specifically Interacts with TRAF2 and Induces Activation of the NF-κB Signaling Pathway

Caspase 8 is required not only for death receptor-mediated apoptosis but also for lymphocyte activation in the immune system. FLIP(L), the long-splice form of c-FLIP, is one of the specific substrates for caspase 8, and increased expression of FLIP(L) promotes activation of the NF-κB signaling pathw...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Kataoka, Takao, Tschopp, Jürg
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371124/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15024054/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.7.2627-2636.2004
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