Asenapine Effects on Cognitive and Monoamine Dysfunction Elicited by Subchronic Phencyclidine Administration

PURPOSE: Repeated, intermittent administration of the psychotropic NMDA antagonist phencyclidine (PCP) to laboratory animals causes impairment in cognitive and executive functions, modeling important sequelae of schizophrenia; these effects are thought to be due to a dysregulation of neurotransmissi...

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Huvudupphovsmän: Elsworth, John D., Groman, Stephanie, Jentsch, J. David, Valles, Rodrigo, Shahid, Mohammed, Wong, Erik, Marston, Hugh, Roth, Robert H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711239/
https://ncbi.nlm.nih.gov/pubmed/21875607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.08.026
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