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Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: Mediating influence of the alpha-2A adrenoceptor subtype

N-methyl-D-aspartic acid/glutamate receptor antagonists induce psychotomimetic effects in humans and animals, and much research has focused on the neurochemical and network-level effects that mediate those behavioral changes. For example, a reduction in NMDA-dependent glutamatergic transmission trig...

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Detalhes bibliográficos
Main Authors: Jentsch, J. David, Sanchez, Diana, Elsworth, John D., Roth, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674271/
https://ncbi.nlm.nih.gov/pubmed/18977208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.10.006
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