Temozolomide-mediated DNA methylation in human myeloid precursor cells:differential involvement of intrinsic and extrinsic apoptotic pathways

PURPOSE: An understanding of how hematopoietic cells respond to therapy that causes myelosuppression will help develop approaches to prevent this potentially life-threatening toxicity. The goal of this study was to determine how human myeloid precursor cells (MP) respond to temozolomide (TMZ)-induce...

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Detalhes bibliográficos
Main Authors: Wang, Haiyan, Cai, Shanbao, Ernstberger, Aaron, Bailey, Barbara J., Wang, Michael Z., Cai, Wenjing, Goebel, W. Scott, Czader, Magdalena B., Crean, Colin, Suvannasankhah, Attaya, Shokolenkoc, Inna, Wilson, Glenn L., Baluyut, Arthur R., Mayo, Lindsey D., Pollok, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711223/
https://ncbi.nlm.nih.gov/pubmed/23536437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2671
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