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Super oxide from NADPH oxidase as second messenger for expression of osteopontin and monocyte chemoattractant-1 in renal epithelial cells exposed to calcium oxalate crystals

OBJECTIVE: Calcium oxalate monohydrate crystals (COM) stimulate OPN and MCP-1 expression in renal tubular cells. Reactive oxygen species (ROS) play an important but not yet fully defined role in expression of inflammatory genes such as MCP-1 and OPN. Recently, it has been proposed that ROS serve as...

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Detalhes bibliográficos
Main Authors: Umekawa, Tohru, Uemura, Hirotsugu, Khan, Saeed R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711191/
https://ncbi.nlm.nih.gov/pubmed/19220254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1464-410X.2009.08374.x
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