Osteopontin knockdown in the kidneys of hyperoxaluric rats leads to reduction in renal calcium oxalate crystal deposition

Osteopontin (OPN) expression is increased in kidneys of rats with ethylene glycol (EG) induced hyperoxaluria and calcium oxalate (CaOx) nephrolithiasis. The aim of this study is to clarify the effect of OPN knockdown by in vivo transfection of OPN siRNA on deposition of CaOx crystals in the kidneys....

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Detalhes bibliográficos
Publicado no:Urolithiasis
Main Authors: Tsuji, Hidenori, Shimizu, Nobutaka, Nozawa, Masahiro, Umekawa, Tohru, Yoshimura, Kazuhiro, De Velasco, Marco A., Uemura, Hirotsugu, Khan, Saeed R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979578/
https://ncbi.nlm.nih.gov/pubmed/24619192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00240-014-0649-0
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