Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes. Effects on activation of NADPH oxidase.

Receptor-mediated agonists, such as FMLP, induce an early, phospholipase D (PLD)-mediated accumulation of phosphatidic acid (PA) which may play a role in the activation of NADPH oxidase in human PMN. We have determined the effect of changes in PA production on O2 consumption in intact PMN and the le...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Agwu, D E, McPhail, L C, Sozzani, S, Bass, D A, McCall, C E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1864964/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115336
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