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Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes. Effects on activation of NADPH oxidase.

Receptor-mediated agonists, such as FMLP, induce an early, phospholipase D (PLD)-mediated accumulation of phosphatidic acid (PA) which may play a role in the activation of NADPH oxidase in human PMN. We have determined the effect of changes in PA production on O2 consumption in intact PMN and the le...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Clin Invest
Principais autores: Agwu, D E, McPhail, L C, Sozzani, S, Bass, D A, McCall, C E
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 1991
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295380/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1864964/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115336
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