PDEF Promotes Luminal Differentiation and Acts as a Survival Factor for ER-Positive Breast Cancer Cells

Breast cancer is a heterogeneous disease and can be classified based on gene expression profiles that reflect distinct epithelial subtypes. We identify prostate derived ETS factor (PDEF) as a mediator of mammary luminal epithelial lineage-specific gene expression and as a factor required for tumorig...

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Detalhes bibliográficos
Main Authors: Buchwalter, Gilles, Hickey, Michele M., Cromer, Anne, Selfors, Laura M., Gunawardane, Ruwanthi N., Frishman, Jason, Jeselsohn, Rinath, Lim, Elgene, Chi, David, Fu, Xiaosong, Schiff, Rachel, Brown, Myles, Brugge, Joan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711136/
https://ncbi.nlm.nih.gov/pubmed/23764000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.04.026
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