Nonnucleoside Inhibitor Binding Affects the Interactions of the Fingers Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase with DNA

Site-directed photoaffinity cross-linking experiments were performed by using human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) mutants with unique cysteine residues at several positions (i.e., positions 65, 67, 70, and 74) in the fingers subdomain of the p66 subunit. Since neit...

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Detalhes bibliográficos
Main Authors: Peletskaya, Elena N., Kogon, Alex A., Tuske, Steven, Arnold, Edward, Hughes, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371094/
https://ncbi.nlm.nih.gov/pubmed/15016861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3387-3397.2004
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