Antiretroviral Drug Resistance Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Increase Template-Switching Frequency

Template-switching events during reverse transcription are necessary for completion of retroviral replication and recombination. Structural determinants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) that influence its template-switching frequency are not known. To identif...

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Bibliographic Details
Published in:J Virol
Main Authors: Nikolenko, Galina N., Svarovskaia, Evguenia S., Delviks, Krista A., Pathak, Vinay K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15280484/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.16.8761-8770.2004
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