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Dynamic copy choice: Steady state between murine leukemia virus polymerase and polymerase-dependent RNase H activity determines frequency of in vivo template switching

We recently proposed a dynamic copy-choice model for retroviral recombination in which a steady state between the rates of polymerization and RNA degradation determines the frequency of reverse transcriptase (RT) template switching. The relative contributions of polymerase-dependent and polymerase-i...

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Detalhes bibliográficos
Main Authors: Hwang, Carey K., Svarovskaia, Evguenia S., Pathak, Vinay K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC59793/
https://ncbi.nlm.nih.gov/pubmed/11593039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221289898
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