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Long Runs of Homozygosity Are Enriched for Deleterious Variation
Exome sequencing offers the potential to study the population-genomic variables that underlie patterns of deleterious variation. Runs of homozygosity (ROH) are long stretches of consecutive homozygous genotypes probably reflecting segments shared identically by descent as the result of processes suc...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710769/ https://ncbi.nlm.nih.gov/pubmed/23746547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.05.003 |
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