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Ancestry-Dependent Enrichment of Deleterious Homozygotes in Runs of Homozygosity
Runs of homozygosity (ROH) are important genomic features that manifest when an individual inherits two haplotypes that are identical by descent. Their length distributions are informative about population history, and their genomic locations are useful for mapping recessive loci contributing to bot...
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| 出版年: | Am J Hum Genet |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6817522/ https://ncbi.nlm.nih.gov/pubmed/31543216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.08.011 |
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