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Long Runs of Homozygosity Are Enriched for Deleterious Variation
Exome sequencing offers the potential to study the population-genomic variables that underlie patterns of deleterious variation. Runs of homozygosity (ROH) are long stretches of consecutive homozygous genotypes probably reflecting segments shared identically by descent as the result of processes suc...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710769/ https://ncbi.nlm.nih.gov/pubmed/23746547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.05.003 |
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