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The Calculation of Free-Energy Differences by Confinement Simulations. Application to Peptide Conformers

Conformational free-energy differences are key quantities for understanding important phenomena in molecular biology that involve large structural changes of macromolecules. In this paper, an improved version of the confinement approach, which is based on earlier developments, determines the free en...

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Detalhes bibliográficos
Main Authors: Cecchini, M., Krivov, S.V., Spichty, M., Karplus, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710665/
https://ncbi.nlm.nih.gov/pubmed/19552392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp9020646
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