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p53-based therapeutics for head and neck squamous cell carcinoma
Inactivation of the tumor suppressor p53 is a pathogenetic event in the development of head and neck squamous cell carcinoma (HNSCC). In the absence of functional wildtype p53, HNSCC cells have increased resistance to standard chemotherapeutics and radiation. Numerous approaches to restore p53 funct...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3710521/ https://ncbi.nlm.nih.gov/pubmed/23623836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2013.03.447 |
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