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Novel p53 therapies for head and neck cancer

Inactivation of the tumor suppressor p53 is the predominant pathogenetic event in head and neck squamous cell carcinoma (HNSCC). The p53 pathway in HNSCC can be compromised through multiple mechanisms including gene mutations, hyperactivation of endogenous negative p53 regulators and by the human pa...

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Detalhes bibliográficos
Publicado no:World J Otorhinolaryngol Head Neck Surg
Main Authors: Castellanos, Mario R., Pan, Quintin
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698513/
https://ncbi.nlm.nih.gov/pubmed/29204550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.wjorl.2016.05.005
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