Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma

The incidence of human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) has rapidly increased over the past 30 years prompting the suggestion that an epidemic may be on the horizon. Therefore, there is a clinical need to develop alternate therapeutic strategies to manage t...

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Hauptverfasser: Xie, Xiujie, Piao, Longzhu, Bullock, Brooke N., Smith, Ashley, Su, Tizhi, Zhang, Manchao, Teknos, Theodoros N., Arora, Paramjit S., Pan, Quintin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912227/
https://ncbi.nlm.nih.gov/pubmed/23474763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.25
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