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Distinct binding properties of TIAR RRMs and linker region

The RNA-binding protein TIAR is an mRNA-binding protein that acts as a translational repressor, particularly important under conditions of cellular stress. It binds to target mRNA and DNA via its RNA recognition motif (RRM) domains and is involved in both splicing regulation and translational repres...

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Detalhes bibliográficos
Main Authors: Kim, Henry S., Headey, Stephen J., Yoga, Yano M.K., Scanlon, Martin J., Gorospe, Myriam, Wilce, Matthew C.J., Wilce, Jacqueline A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710364/
https://ncbi.nlm.nih.gov/pubmed/23603827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.24341
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