Different modes of interaction by TIAR and HuR with target RNA and DNA

TIAR and HuR are mRNA-binding proteins that play important roles in the regulation of translation. They both possess three RNA recognition motifs (RRMs) and bind to AU-rich elements (AREs), with seemingly overlapping specificity. Here we show using SPR that TIAR and HuR bind to both U-rich and AU-ri...

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Hlavní autoři: Kim, Henry S., Wilce, Matthew C. J., Yoga, Yano M. K., Pendini, Nicole R., Gunzburg, Menachem J., Cowieson, Nathan P., Wilson, Gerald M., Williams, Bryan R. G., Gorospe, Myriam, Wilce, Jacqueline A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Structural Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035456/
https://ncbi.nlm.nih.gov/pubmed/21233170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq837
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