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β-adrenergic stimulation increases the intra-SR Ca termination threshold for spontaneous Ca waves in cardiac myocytes

β-adrenergic stimulation of cardiac myocytes enhances intracellular calcium cycling, which frequently associates with pro-arrhythmic Ca waves. The threshold level of free calcium in the sarcoplasmic reticulum ([Ca](SR)) where waves initiate is increased during β-adrenergic stimulation.(1) Here, we m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Maxwell, Joshua T., Domeier, Timothy L., Blatter, Lothar A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710347/
https://ncbi.nlm.nih.gov/pubmed/23510939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.24173
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