Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease

BACKGROUND: Vitamin D insufficiency has been implicated in autoimmunity. ChIP-seq experiments using immune cell lines have shown that vitamin D receptor (VDR) binding sites are enriched near regions of the genome associated with autoimmune diseases. We aimed to investigate VDR binding in primary CD4...

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Hlavní autoři: Handel, Adam E, Sandve, Geir K, Disanto, Giulio, Berlanga-Taylor, Antonio J, Gallone, Giuseppe, Hanwell, Heather, Drabløs, Finn, Giovannoni, Gavin, Ebers, George C, Ramagopalan, Sreeram V
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710212/
https://ncbi.nlm.nih.gov/pubmed/23849224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-11-163
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