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Integrating multiple oestrogen receptor alpha ChIP studies: overlap with disease susceptibility regions, DNase I hypersensitivity peaks and gene expression

BACKGROUND: A wealth of nuclear receptor binding data has been generated by the application of chromatin immunoprecipitation (ChIP) techniques. However, there have been relatively few attempts to apply these datasets to human complex disease or traits. METHODS: We integrated multiple oestrogen recep...

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Vydáno v:BMC Med Genomics
Hlavní autoři: Handel, Adam E, Sandve, Geir K, Disanto, Giulio, Handunnetthi, Lahiru, Giovannoni, Gavin, Ramagopalan, Sreeram V
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228442/
https://ncbi.nlm.nih.gov/pubmed/24171864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-45
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