Dysmorphic Photoreceptors in a P23H Mutant Rhodopsin Model of Retinitis Pigmentosa Are Metabolically Active and Capable of Regenerating to Reverse Retinal Degeneration

This study evaluated the capacity of Xenopus laevis retina to regenerate photoreceptor cells after cyclic light-mediated acute rod photoreceptor degeneration in a transgenic P23H mutant rhodopsin model of retinits pigmentosa. After discontinuation of cyclic light exposure, we monitored histologic pr...

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Autors principals: Lee, Damian C., Vazquez-Chona, Felix R., Ferrell, W. Drew, Tam, Beatrice M., Jones, Bryan W., Marc, Robert E., Moritz, Orson L.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710121/
https://ncbi.nlm.nih.gov/pubmed/22323724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4752-11.2012
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