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Secondary structure of the HIV reverse transcription initiation complex by NMR

Initiation of reverse transcription of genomic RNA is a key early step in replication of the human immunodeficiency virus (HIV) upon infection of a host cell. Viral reverse transcriptase (RT) initiates from a specific RNA-RNA complex formed between a host transfer RNA (tRNA(Lys)(3)) and region at th...

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Bibliographic Details
Main Authors: Puglisi, Elisabetta Viani, Puglisi, Joseph D.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710119/
https://ncbi.nlm.nih.gov/pubmed/21763492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.024
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