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Architecture of an HIV-1 reverse transcriptase initiation complex
Reverse transcription of the HIV-1 RNA genome into double-stranded DNA is a central step in infection(1) and a common target of antiretrovirals(2). The reaction is catalyzed by viral reverse transcriptase (RT)(3,4) that is packaged in an infectious virion along with 2 copies of dimeric viral genomic...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5934294/ https://ncbi.nlm.nih.gov/pubmed/29695867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0055-9 |
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