Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor

Proteoglycans like syndecan-3 have complex signaling roles in addition to their function as structural components of the extracellular matrix. Here, we show that syndecan-3 in the lateral hypothalamus has an unexpected new role in limiting compulsive cocaine intake. In particular, we observe that sy...

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Autors principals: Chen, Jihuan, Repunte-Canonigo, Vez, Kawamura, Tomoya, Lefebvre, Celine, Shin, William, Howell, Leonard L., Hemby, Scott E., Harvey, Brandon K., Califano, Andrea, Morales, Marisela, Koob, George F., Sanna, Pietro Paolo
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709481/
https://ncbi.nlm.nih.gov/pubmed/23736082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2955
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