Charge Characteristics of Agouti-Related Protein Implicate Potent Involvement of Heparan Sulfate Proteoglycans in Metabolic Function

The endogenous melanocortin peptide agouti-related protein (AgRP) plays a well-known role in foraging, but its contribution to metabolic regulation is less understood. Mature AgRP((83-132)) has distinct residues for melanocortin receptor binding and heparan sulfate interactions. Here, we show that A...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:iScience
Main Authors: Chen, Jihuan, Chen, Valerie, Kawamura, Tomoya, Hoang, Ivy, Yang, Yang, Wong, Ashley Tess, McBride, Ryan, Repunte-Canonigo, Vez, Millhauser, Glenn L., Sanna, Pietro Paolo
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6928319/
https://ncbi.nlm.nih.gov/pubmed/31863782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.10.061
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker