CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress

CCN2 (connective tissue growth factor (CTGF/CCN2)) is a matricellular protein that utilizes integrins to regulate cell proliferation, migration and survival. The loss of CCN2 leads to perinatal lethality resulting from a severe chondrodysplasia. Upon closer inspection of Ccn2 mutant mice, we observe...

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Detalhes bibliográficos
Main Authors: Hall-Glenn, Faith, Aivazi, Armen, Akopyan, Lusi, Ong, Jessica R., Baxter, Ruth R., Benya, Paul D., Goldschmeding, Roel, van Nieuwenhoven, Frans A., Hunziker, Ernst B., Lyons, Karen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709047/
https://ncbi.nlm.nih.gov/pubmed/23666466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-013-0201-y
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