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Stage-specific Control of Connective Tissue Growth Factor (CTGF/CCN2) Expression in Chondrocytes by Sox9 and β-Catenin

CCN2/connective tissue growth factor is highly expressed in hypertrophic chondrocytes and is required for chondrogenesis. However, the transcriptional mechanisms controlling its expression in cartilage are largely unknown. The activity of the Ccn2 promoter was, therefore, investigated in osteochondr...

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Bibliografiske detaljer
Main Authors: Huang, Bau-Lin, Brugger, Sean M., Lyons, Karen M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934638/
https://ncbi.nlm.nih.gov/pubmed/20571031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.108498
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