CCN family 2/connective tissue growth factor (CCN2/CTGF) regulates the expression of Vegf through Hif-1α expression in a chondrocytic cell line, HCS-2/8, under hypoxic condition

Vascular endothelial growth factor (VEGF) is essential for establishing vascularization and regulating chondrocyte development and survival. We have demonstrated that VEGF regulates the expression of CCN2/connective tissue growth factor (CCN2/CTGF) an essential mediator of cartilage development and...

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Autors principals: Nishida, Takashi, Kondo, Seiji, Maeda, Azusa, Kubota, Satoshi, Lyons, Karen M, Takigawa, Masaharu
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760594/
https://ncbi.nlm.nih.gov/pubmed/18835464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2008.08.125
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