CCN Family 2/Connective Tissue Growth Factor Modulates BMP Signalling as a Signal Conductor, Which Action Regulates the Proliferation and Differentiation of Chondrocytes

Both CCN family 2/connective tissue growth factor (CCN2/CTGF) and bone morphogenetic protein (BMP)-2 play an important role in cartilage metabolism. We evaluated whether or not CCN2 would interact with BMP-2, and examined the combination effect of CCN2 with BMP-2 (CCN2-BMP-2) on the proliferation an...

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Detalhes bibliográficos
Main Authors: Maeda, Azusa, Nishida, Takashi, Aoyama, Eriko, Kubota, Satoshi, Lyons, Karen M., Kuboki, Takuo, Takigawa, Masaharu
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760593/
https://ncbi.nlm.nih.gov/pubmed/19038999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvn159
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