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The Efficiency of Homologous Recombination and Non-Homologous End Joining Systems in Repairing Double-Strand Breaks during Cell Cycle Progression

This study investigated the efficiency of Non-Homologous End Joining (NHEJ) and Homologous Recombination (HR) repair systems in rejoining DNA double-strand breaks (DSB) induced in CCD-34Lu cells by different γ-ray doses. The kinetics of DNA repair was assessed by analyzing the fluorescence decrease...

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Main Authors: Bee, Leonardo, Fabris, Sonia, Cherubini, Roberto, Mognato, Maddalena, Celotti, Lucia
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708908/
https://ncbi.nlm.nih.gov/pubmed/23874869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069061
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