INI1/hSNF5-interaction defective HIV-1 IN mutants exhibit impaired particle morphology, reverse transcription and integration in vivo

BACKGROUND: Retroviral integrase catalyzes integration of viral DNA into the host genome. Integrase interactor (INI)1/hSNF5 is a host factor that binds to HIV-1 IN within the context of Gag-Pol and is specifically incorporated into HIV-1 virions during assembly. Previous studies have indicated that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mathew, Sheeba, Nguyen, Minh, Wu, Xuhong, Pal, Achintya, Shah, Vaibhav B, Prasad, Vinayaka R, Aiken, Christopher, Kalpana, Ganjam V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708822/
https://ncbi.nlm.nih.gov/pubmed/23799881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-66
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados