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Inhibition of Early Stages of HIV-1 Assembly by INI1/hSNF5 Transdominant Negative Mutant S6

INI1/hSNF5 is an HIV-1 integrase (IN) binding protein specifically incorporated into virions. A truncated mutant of INI1 (S6, amino acids 183 to 294) harboring the minimal IN binding Rpt1 domain potently inhibits HIV-1 particle production in a transdominant manner. The inhibition requires interactio...

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Bibliografiske detaljer
Main Authors: Cano, Jennifer, Kalpana, Ganjam V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067803/
https://ncbi.nlm.nih.gov/pubmed/21159874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00006-10
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