HIV-1 replication in cell lines harboring INI1/hSNF5 mutations

BACKGROUND: INI1/hSNF5 is a cellular protein that directly interacts with HIV-1 integrase (IN). It is specifically incorporated into HIV-1 virions. A dominant negative mutant derived from INI1 inhibits HIV-1 replication. Recent studies indicate that INI1 is associated with pre-integration and revers...

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Bibliographic Details
Main Authors: Sorin, Masha, Yung, Eric, Wu, Xuhong, Kalpana, Ganjam V
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592304/
https://ncbi.nlm.nih.gov/pubmed/16945155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-56
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