Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

BACKGROUND: Glaucoma is an age-related neurodegenerative disorder involving the loss of retinal ganglion cells (RGCs), which results in blindness. Studies in animal models have shown that activation of inflammatory processes occurs early in the disease. In particular, the complement cascade is activ...

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Main Authors: Howell, Gareth R, Soto, Ileana, Ryan, Margaret, Graham, Leah C, Smith, Richard S, John, Simon WM
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708765/
https://ncbi.nlm.nih.gov/pubmed/23806181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-76
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