Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1

BACKGROUND: The glaucomas are a common but incompletely understood group of diseases. DBA/2J mice develop a pigment liberating iris disease that ultimately causes elevated intraocular pressure (IOP) and glaucoma. We have shown previously that mutations in two genes, Gpnmb and Tyrp1, initiate the iri...

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Autors principals: Howell, Gareth R, Libby, Richard T, Marchant, Jeffrey K, Wilson, Lawriston A, Cosma, Ioan M, Smith, Richard S, Anderson, Michael G, John, Simon WM
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1937007/
https://ncbi.nlm.nih.gov/pubmed/17608931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-8-45
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