Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

Phagocytosis is a fundamental cellular process that is pivotal for immunity as it coordinates microbial killing, innate immune activation and antigen presentation. An essential step in this process is phagosome acidification, which regulates a number of functions of these organelles that allow them...

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Hlavní autoři: Sokolovska, Anna, Becker, Christine E., Eddie Ip, WK, Rathinam, Vijay A.K., Brudner, Matthew, Paquette, Nicholas, Tanne, Antoine, Vanaja, Sivapriya K., Moore, Kathryn J., Fitzgerald, Katherine A., Lacy-Hulbert, Adam, Stuart, Lynda M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708594/
https://ncbi.nlm.nih.gov/pubmed/23644505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2595
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