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Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma
BACKGROUND: Autophagy is a lysosomal degradation pathway that can provide energy through its recycling mechanism to act as a cytoprotective adaptive response mediating treatment resistance in cancer cells. We investigated the autophagy-inducing effects of ZD6474, a small-molecule inhibitor that bloc...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708568/ https://ncbi.nlm.nih.gov/pubmed/23799852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.306 |
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