Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma

BACKGROUND: Autophagy is a lysosomal degradation pathway that can provide energy through its recycling mechanism to act as a cytoprotective adaptive response mediating treatment resistance in cancer cells. We investigated the autophagy-inducing effects of ZD6474, a small-molecule inhibitor that bloc...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Shen, J, Zheng, H, Ruan, J, Fang, W, Li, A, Tian, G, Niu, X, Luo, S, Zhao, P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Molecular Diagnostics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708568/
https://ncbi.nlm.nih.gov/pubmed/23799852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.306
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