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Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit

The central nonsense-mediated mRNA decay (NMD) regulator, Upf1, selectively targets nonsense-containing mRNAs for rapid degradation. In yeast, Upf1 preferentially associates with mRNAs that are NMD substrates, but the mechanism of its selective retention on these mRNAs has yet to be elucidated. Prev...

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Autori principali: Min, Ei Ei, Roy, Bijoyita, Amrani, Nadia, He, Feng, Jacobson, Allan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708530/
https://ncbi.nlm.nih.gov/pubmed/23801788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.039396.113
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