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Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit
The central nonsense-mediated mRNA decay (NMD) regulator, Upf1, selectively targets nonsense-containing mRNAs for rapid degradation. In yeast, Upf1 preferentially associates with mRNAs that are NMD substrates, but the mechanism of its selective retention on these mRNAs has yet to be elucidated. Prev...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708530/ https://ncbi.nlm.nih.gov/pubmed/23801788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.039396.113 |
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