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Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit

The central nonsense-mediated mRNA decay (NMD) regulator, Upf1, selectively targets nonsense-containing mRNAs for rapid degradation. In yeast, Upf1 preferentially associates with mRNAs that are NMD substrates, but the mechanism of its selective retention on these mRNAs has yet to be elucidated. Prev...

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Autors principals: Min, Ei Ei, Roy, Bijoyita, Amrani, Nadia, He, Feng, Jacobson, Allan
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708530/
https://ncbi.nlm.nih.gov/pubmed/23801788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.039396.113
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