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Yeast Upf1 CH domain interacts with Rps26 of the 40S ribosomal subunit

The central nonsense-mediated mRNA decay (NMD) regulator, Upf1, selectively targets nonsense-containing mRNAs for rapid degradation. In yeast, Upf1 preferentially associates with mRNAs that are NMD substrates, but the mechanism of its selective retention on these mRNAs has yet to be elucidated. Prev...

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Detalhes bibliográficos
Main Authors: Min, Ei Ei, Roy, Bijoyita, Amrani, Nadia, He, Feng, Jacobson, Allan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708530/
https://ncbi.nlm.nih.gov/pubmed/23801788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.039396.113
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