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Ro60 Requires Y3 RNA for Cell Surface Exposure and Inflammation Associated with Cardiac Manifestations of Neonatal Lupus

Cardiac neonatal lupus (NL) is presumed to arise from maternal autoantibody targeting an intracellular ribonucleoprotein, Ro60, which binds noncoding Y RNA and only becomes accessible to autoantibodies during apoptosis. Despite the importance of Ro60 trafficking in the development of cardiac-NL, the...

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書誌詳細
主要な著者: Reed, Joanne H., Sim, Soyeong, Wolin, Sandra L., Clancy, Robert M., Buyon, Jill P.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708308/
https://ncbi.nlm.nih.gov/pubmed/23698747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202849
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