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Noncoding Y RNAs regulate the levels, subcellular distribution and protein interactions of their Ro60 autoantigen partner

Noncoding Y RNAs are abundant in animal cells and present in many bacteria. These RNAs are bound and stabilized by Ro60, a ring-shaped protein that is a target of autoantibodies in patients with systemic lupus erythematosus. Studies in bacteria revealed that Y RNA tethers Ro60 to a ring-shaped exori...

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Foilsithe in:Nucleic Acids Res
Main Authors: Leng, Yuanyuan, Sim, Soyeong, Magidson, Valentin, Wolin, Sandra L
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337961/
https://ncbi.nlm.nih.gov/pubmed/32469055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa414
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