Beta2-glycoprotein-I and Protection from Anti-SSA/Ro 60 Associated Cardiac Manifestations of Neonatal Lupus

One mechanism to molecularly explain the strong association of maternal anti-Ro60 antibodies with cardiac disease in neonatal lupus (NL) is that these antibodies initiate injury by binding to apoptotic cardiomyocytes in the fetal heart. Previous studies have demonstrated that beta2-glycoprotein I (β...

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Hauptverfasser: Reed, Joanne H., Clancy, Robert M., Purcell, Anthony W., Kim, Mimi Y., Gordon, Tom P., Buyon, Jill P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129650/
https://ncbi.nlm.nih.gov/pubmed/21602492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100122
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